Automated Design of Diverse Stand-Alone Riboswitches
نویسندگان
چکیده
منابع مشابه
Automated physics-based design of synthetic riboswitches from diverse RNA aptamers.
Riboswitches are shape-changing regulatory RNAs that bind chemicals and regulate gene expression, directly coupling sensing to cellular actuation. However, it remains unclear how their sequence controls the physics of riboswitch switching and activation, particularly when changing the ligand-binding aptamer domain. We report the development of a statistical thermodynamic model that predicts the...
متن کاملStand-alone automated solutions can enhance laboratory operations.
Clinical laboratory automation has developed over the past decade as one means of consolidating testing, reducing costs, and improving the effectiveness of laboratory testing. Most of the developments have been aimed at core clinical laboratory operations, and have primarily addressed preanalytical and analytical processing of traditional specimens arriving in blood collection or similar aliquo...
متن کاملOptimal Configuration for Design of Stand-Alone PV System
This paper presents a design for a stand-alone photovoltaic (PV) system to provide the required electricity for a single residential household in rural area in Jordan. The complete design steps for the suggested household loads are carried out. Site radiation data and the electrical load data of a typical household in the considered site are taken into account during the design steps. The relia...
متن کاملWhy science cannot stand alone.
In an era in which certain arenas of scientific research have become increasingly controversial, this article critically evaluates what it means to "believe in science." Many scientists today seem to claim a sovereign right to no political interference under the rubric of freedom. This article questions such a notion, and explores the dominance of science and the silencing of moral voices by un...
متن کاملConfidence Stand-alone Sw Systems
CONFIDENCE Ubiquitous Care System to Support Independent Living is one of the most interesting FP7 projects for The department of intelligent systems at JSI. In this paper we present WP3, the major SW component of the system that is also implemented as two stand-alone versions of the system. In this paper, the two systems are presented from the user viewpoint based on five manuals.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Synthetic Biology
سال: 2019
ISSN: 2161-5063,2161-5063
DOI: 10.1021/acssynbio.9b00142